Firms, funds, partners, companies and rounds from sworn filings, firm sites and announcements, kept as a graph with a date and a source on every edge. Facts, inferences and estimates are labelled as such. A fund target is never a close, GAV is never dry powder, and a round size is never an investor’s check.

Firms / NEW Leaf Venture Partners

NEW Leaf Venture Partners

Multi-stage venture firm · probableNew York, NYnlvpartners.comSEC registered investment adviser

both early and growth/opportunity families, reported GAV $662M

Importance
44
elevated
Active deployment
55
elevated
Emerging
0
low
Completeness
63
high
Freshness
100
high
Research priority
22
moderate
Identity and regulatory footprint
Headquarters
New York, NYadviserinfo.sec.gov
Office address
156 FIFTH AVENUE, SUITE 820, New York, NY, 10010adviserinfo.sec.gov
Business phone
646-871-6420adviserinfo.sec.gov
SEC adviser type
registered investment adviseradviserinfo.sec.gov
SEC exemption claimed
unknown
Latest Form ADV
Mar 30, 2026
Private funds reported
9 (9 venture capital funds)adviserinfo.sec.gov
Private fund gross assets
$408Madviserinfo.sec.govreported GAV of the funds, the adviser's own number; not fund size, not dry powder
Regulatory AUM
$408Mthe adviser's RAUM, a regulatory measure, never a fund size
Employees
4
Owners on Schedule A
NLV Partners Management GP, LLC (Active), F; NEW Leaf Venture Partners Holdings, L.P. (Member), E
business email
info@nlvpartners.comnlvpartners.compublished by the subject
business email
craig@nlvpartners.comnlvpartners.compublished by the subject
business phone
646-871-6420adviserinfo.sec.govpublished by the subject
Stated thesis versus observed behaviour
12 observed deals
Stated (the firm’s website)
Sectors
healthcare
Stages
not stated or not yet read
Geography
not stated
Check size
not stated; DFX does not estimate checks from round sizes
Observed (from deals on record)
Stage at participation: no observed deals yet
Stage at first entry: no observed deals yet
Sectors
unknown 58%Biotechnology 17%Other Technology 17%Other 8%
lead rate n/afollow-on rate n/anew logos, 12 months 12
Funds and vehicles
11 reported, 1 no longer reported
VehicleTypeVintageLifecycleReported GAVOwnersForm D soldLatest Form D
Nlv-Ii Spv-2, L.P.SPV or co-invest vehicle2024 adv first reportedEarly deployment$78.7M
Mar 28, 2024
2$0Nov 13, 2023
Nlv-Ii Spv-1, L.P.SPV or co-invest vehicle2024 adv first reportedEarly deployment$78.4M
Mar 28, 2024
14$0Nov 13, 2023
NLV Co-Invest III, LLCSPV or co-invest vehicle2022 adv first reportedActive deployment$9.1M
Mar 28, 2024
1unknownunknown
NLV Co-Invest II, LLCSPV or co-invest vehicle2021 adv first reportedMature$5.3M
Mar 28, 2024
3unknownunknown
NEW Leaf Ventures IV, L.P.Fund2019 adv first reportedMature$160M
Mar 28, 2024
15$0
of $275M
Apr 16, 2018
NEW Leaf Biopharma Opportunities II, L.P.Opportunity fund2019 adv first reportedMature$130M
Mar 28, 2024
9$0
of $200M
Apr 16, 2018
NEW Leaf Ventures III, L.P.Fund2014 adv first reportedHarvest$179M
Mar 28, 2024
34unknownunknown
NEW Leaf Growth Fund I, L.P.Growth fund2014 adv first reportedHarvest$10.0M
Mar 28, 2024
2$0Dec 3, 2014
NLV Partners Co-Invest I, LLCSPV or co-invest vehicle2014 adv first reportedHarvest$8.0M
Mar 30, 2022
2unknownunknown
NEW Leaf Ventures I, L.P.FundunknownUnknown$3.9M
Mar 28, 2024
46unknownunknown
NEW Leaf Venture PartnersFundunknownUnknownunknownunknown$0
of $375M
Dec 3, 2014
NEW Leaf Ventures II, L.P.FundunknownWound down$75.6M
Mar 31, 2023
57unknownunknown
GAV is the gross asset value the adviser reported on Form ADV for the vehicle, never the fund’s committed size and never dry powder. Form D sold is the amount sold as of the latest filing, never a final close.
Investment team
6 current, 7 departed
7 departed (kept with end dates)
  • Isaac Manke · General Partner · Apr 1, 2018 to Mar 18, 2020 Inference
  • Jeani C. Delagardelle · Active · Jul 1, 2005 to Mar 28, 2018 Inference
  • Liam T Ratcliffe · Active · Jun 1, 2014 to Apr 22, 2019 Inference
  • James E Niedel · Managing Director And Member · Jul 1, 2005 to Dec 19, 2014 Inference
  • Philippe Chambon · Managing Director · Jul 1, 2005 to Apr 3, 2017 Inference
  • Select Page · Co-Founder/Managing Director · ? to Sep 16, 2026 Inference
  • Srinivas Akkaraju · Managing Director And Member · Jan 1, 2009 to May 17, 2013 Inference
Investments on record
12 edges, 12 companies, 0 partner-attributed
CompanyRoundRolePartnerRound sizeThis investorDateSource
Abcuro, Inc.portfolio listingunknownunknownunknownunknownSep 16, 2026Fact Venture organization websites (about, team, portfolio, thesis, news pages)
BrightInsightportfolio listingunknownunknownunknownunknownSep 16, 2026Fact Venture organization websites (about, team, portfolio, thesis, news pages)
Cleerly, Inc.portfolio listingunknownunknownunknownunknownSep 16, 2026Fact Venture organization websites (about, team, portfolio, thesis, news pages)
Cogent Biosciencesportfolio listingunknownunknownunknownunknownSep 16, 2026Fact Venture organization websites (about, team, portfolio, thesis, news pages)
Dice Therapeuticsportfolio listingunknownunknownunknownunknownSep 16, 2026Fact Venture organization websites (about, team, portfolio, thesis, news pages)
Electra Therapeutics, Inc.portfolio listingunknownunknownunknownunknownSep 16, 2026Fact Venture organization websites (about, team, portfolio, thesis, news pages)
Escape Bioportfolio listingunknownunknownunknownunknownSep 16, 2026Fact Venture organization websites (about, team, portfolio, thesis, news pages)
Flosonicsportfolio listingunknownunknownunknownunknownSep 16, 2026Fact Venture organization websites (about, team, portfolio, thesis, news pages)
Kalderos, Inc.portfolio listingunknownunknownunknownunknownSep 16, 2026Fact Venture organization websites (about, team, portfolio, thesis, news pages)
Rocket Pharmaportfolio listingunknownunknownunknownunknownSep 16, 2026Fact Venture organization websites (about, team, portfolio, thesis, news pages)
Star Therapeutics LLCportfolio listingunknownunknownunknownunknownSep 16, 2026Fact Venture organization websites (about, team, portfolio, thesis, news pages)
Sunbird Bioportfolio listingunknownunknownunknownunknownSep 16, 2026Fact Venture organization websites (about, team, portfolio, thesis, news pages)
“This investor” is the amount disclosed for this investor alone; it is unknown unless a source said it. The round size is the whole round.
Co-investors
6 relationships from shared deals, counted for the whole firm
Limited partners
0 disclosed
No LP commitment on record. An LP edge needs a public disclosure with a quote: a pension report (see Limited partners for the plans read), a fund announcement naming the LP, or a Form ADV owner. The fund page carries the LP’s reported performance.
Timeline
23 dated events
  1. Sep 16, 2026
    Select Page (Co-Founder/Managing Director) no longer on the team page of NEW Leaf Venture Partners
  2. Mar 28, 2024
    Nlv-Ii Spv-1, L.P. first reported on Form ADV by NEW Leaf Venture Partners (Venture Capital Fund), GAV $78,351,470
  3. Mar 28, 2024
    NEW Leaf Ventures II, L.P. no longer reported on Form ADV by NEW Leaf Venture Partners
  4. Mar 28, 2024
    Nlv-Ii Spv-2, L.P. first reported on Form ADV by NEW Leaf Venture Partners (Venture Capital Fund), GAV $78,653,856
  5. Mar 30, 2022
    NLV Co-Invest III, LLC first reported on Form ADV by NEW Leaf Venture Partners (Venture Capital Fund), GAV $17,308,629
  6. Mar 25, 2021
    NLV Co-Invest II, LLC first reported on Form ADV by NEW Leaf Venture Partners (Private Equity Fund), GAV $7,999,995
  7. Mar 18, 2020
    Isaac Manke (General Partner) no longer on Schedule A of NEW Leaf Venture Partners
  8. Apr 22, 2019
    Liam Thomas Ratcliffe (Active) no longer on Schedule A of NEW Leaf Venture Partners
  9. Mar 29, 2019
    NEW Leaf Ventures IV, L.P. first reported on Form ADV by NEW Leaf Venture Partners (Venture Capital Fund), GAV $18,492,482
  10. Mar 29, 2019
    NEW Leaf Biopharma Opportunities II, L.P. first reported on Form ADV by NEW Leaf Venture Partners (Venture Capital Fund), GAV $73,806,254
  11. Apr 1, 2018
    Isaac Manke joined Schedule A of NEW Leaf Venture Partners as General Partner
  12. Mar 28, 2018
    Jeani Camarano Delagardelle (Active) no longer on Schedule A of NEW Leaf Venture Partners
  13. Apr 3, 2017
    Philippe Olaf Chambon (Managing Director) no longer on Schedule A of NEW Leaf Venture Partners
  14. Dec 19, 2014
    NEW Leaf Ventures III, L.P. first reported on Form ADV by NEW Leaf Venture Partners (Venture Capital Fund)
  15. Dec 19, 2014
    NLV Partners Co-Invest I, LLC first reported on Form ADV by NEW Leaf Venture Partners (Venture Capital Fund), GAV $2,000,000
  16. Dec 19, 2014
    James E Niedel (Managing Director And Member) no longer on Schedule A of NEW Leaf Venture Partners
  17. Dec 19, 2014
    NEW Leaf Growth Fund I, L.P. first reported on Form ADV by NEW Leaf Venture Partners (Venture Capital Fund)
  18. Dec 3, 2014
    New Leaf Ventures III, L.P. filed Form D: no sales yet of $375,000,000, Private Equity Fund
    Form D filedFundraisingFactSEC EDGAR Form D data sets (quarterly)
  19. Jun 1, 2014
    Liam T Ratcliffe joined Schedule A of NEW Leaf Venture Partners as Managing Director And Member
  20. May 17, 2013
    Srinivas Akkaraju (Managing Director And Member) no longer on Schedule A of NEW Leaf Venture Partners
  21. Apr 9, 2012
    NEW Leaf Venture Partners first filed Form ADV (ERA, venture capital fund adviser exemption)
  22. Apr 9, 2012
    NEW Leaf Ventures II, L.P. first reported on Form ADV by NEW Leaf Venture Partners (Venture Capital Fund), GAV $410,650,867
  23. Apr 9, 2012
    NEW Leaf Ventures I, L.P. first reported on Form ADV by NEW Leaf Venture Partners (Venture Capital Fund), GAV $199,587,303
Classification history
  1. Sep 15, 2026
    Multi-stage venture firm (probable, 80%, cls-1)
    both early and growth/opportunity families, reported GAV $662M
  2. Sep 12, 2026
    Multi-stage venture firm (probable, 80%, cls-1)
    both early and growth/opportunity families, reported GAV $584M
Evidence
75 observations from 4 sources
Every observation behind this profile, with its source, date and class
FactValueEffectiveClassSource
Why admittedvc_funds_reportedMar 30, 2026FactSEC Form ADV monthly roster (registered + exempt reporting advisers)
SEC adviser typeregistered_investment_adviserMar 30, 2026FactSEC Form ADV monthly roster (registered + exempt reporting advisers)
SEC adviser typeregistered_investment_adviserMar 28, 2024FactSEC Form ADV filing data 2011 to 2024 (every filing, Schedule D 7.B.(1) private funds, Schedules A/B)
First Form ADV filing2012-04-09Mar 28, 2024FactSEC Form ADV filing data 2011 to 2024 (every filing, Schedule D 7.B.(1) private funds, Schedules A/B)
Adv history loadedadv-hist-1Sep 12, 2026FactSEC Form ADV filing data 2011 to 2024 (every filing, Schedule D 7.B.(1) private funds, Schedules A/B)
Latest Form ADV filing2026-03-30Mar 30, 2026FactSEC Form ADV monthly roster (registered + exempt reporting advisers)
Latest Form ADV filing2024-03-28Mar 28, 2024FactSEC Form ADV filing data 2011 to 2024 (every filing, Schedule D 7.B.(1) private funds, Schedules A/B)
SEC statusApprovedMar 30, 2026FactSEC Form ADV monthly roster (registered + exempt reporting advisers)
SEC status effective2015-01-15Mar 30, 2026FactSEC Form ADV monthly roster (registered + exempt reporting advisers)
Venture share of reported funds1Mar 28, 2024FactSEC Form ADV filing data 2011 to 2024 (every filing, Schedule D 7.B.(1) private funds, Schedules A/B)
Business phone646-871-6420Mar 30, 2026FactSEC Form ADV monthly roster (registered + exempt reporting advisers)
Business phone646-871-6420Mar 28, 2024FactSEC Form ADV filing data 2011 to 2024 (every filing, Schedule D 7.B.(1) private funds, Schedules A/B)
Contact page urlhttps://www.nlvpartners.com/contact/
contact page linked from the home page
Sep 16, 2026FactVenture organization websites (about, team, portfolio, thesis, news pages)
Employees4Mar 30, 2026FactSEC Form ADV monthly roster (registered + exempt reporting advisers)
Employees5Mar 28, 2024FactSEC Form ADV filing data 2011 to 2024 (every filing, Schedule D 7.B.(1) private funds, Schedules A/B)
Entity typeLimited PartnershipDec 3, 2014FactSEC EDGAR Form D data sets (quarterly)
Form D fund typePrivate Equity FundDec 3, 2014FactSEC EDGAR Form D data sets (quarterly)
Form D industry groupPooled Investment FundDec 3, 2014FactSEC EDGAR Form D data sets (quarterly)
AmendmentfalseDec 3, 2014FactSEC EDGAR Form D data sets (quarterly)
Revenue range (Form D)Not ApplicableDec 3, 2014FactSEC EDGAR Form D data sets (quarterly)
HeadquartersNew York, NYMar 30, 2026FactSEC Form ADV monthly roster (registered + exempt reporting advisers)
HeadquartersNew York, NYMar 28, 2024FactSEC Form ADV filing data 2011 to 2024 (every filing, Schedule D 7.B.(1) private funds, Schedules A/B)
IncorporatedwithinFiveYearsDec 3, 2014FactSEC EDGAR Form D data sets (quarterly)
JurisdictionDELAWAREDec 3, 2014FactSEC EDGAR Form D data sets (quarterly)
Amount sold (Form D)0Dec 3, 2014FactSEC EDGAR Form D data sets (quarterly)
Offering amount (Form D)375,000,000Dec 3, 2014FactSEC EDGAR Form D data sets (quarterly)
Exemptions06b, 3C, 3C.7Dec 3, 2014FactSEC EDGAR Form D data sets (quarterly)
Investors (Form D)0Dec 3, 2014FactSEC EDGAR Form D data sets (quarterly)
Minimum investment (Form D)0Dec 3, 2014FactSEC EDGAR Form D data sets (quarterly)
Securities offeredpooledDec 3, 2014FactSEC EDGAR Form D data sets (quarterly)
Office address156 FIFTH AVENUE, SUITE 820, New York, NY, 10010Mar 30, 2026FactSEC Form ADV monthly roster (registered + exempt reporting advisers)
Office address156 FIFTH AVENUE, SUITE 820, New York, NY, 10010Mar 28, 2024FactSEC Form ADV filing data 2011 to 2024 (every filing, Schedule D 7.B.(1) private funds, Schedules A/B)
Office addressC/O NEW LEAF VENTURE PARTNERS, 7 TIMES SQUARE, SUITE 3502, NEW YORK, NY, 10036Dec 3, 2014FactSEC EDGAR Form D data sets (quarterly)
Legal formLimited Liability CompanyMar 30, 2026FactSEC Form ADV monthly roster (registered + exempt reporting advisers)
Portfolio pagehttps://www.nlvpartners.com/portfolio/
15 entries read
Sep 16, 2026FactVenture organization websites (about, team, portfolio, thesis, news pages)
Portfolio pagehttps://www.nlvpartners.com/portfolio/
15 entries read
Sep 12, 2026FactVenture organization websites (about, team, portfolio, thesis, news pages)
Private funds reported9Mar 30, 2026FactSEC Form ADV monthly roster (registered + exempt reporting advisers)
Private funds reported9Mar 28, 2024FactSEC Form ADV filing data 2011 to 2024 (every filing, Schedule D 7.B.(1) private funds, Schedules A/B)
Private fund gross assets (reported)$408MMar 30, 2026FactSEC Form ADV monthly roster (registered + exempt reporting advisers)
Private fund gross assets (reported)$654MMar 28, 2024FactSEC Form ADV filing data 2011 to 2024 (every filing, Schedule D 7.B.(1) private funds, Schedules A/B)
Regulatory AUM (adviser, not fund size)$408MMar 30, 2026FactSEC Form ADV monthly roster (registered + exempt reporting advisers)
Regulatory AUM (adviser, not fund size)$580MMar 28, 2024FactSEC Form ADV filing data 2011 to 2024 (every filing, Schedule D 7.B.(1) private funds, Schedules A/B)
Stated sectorshealthcare
sector words on the home page
Sep 16, 2026FactVenture organization websites (about, team, portfolio, thesis, news pages)
Stated sectorshealthcare
sector words on the home page
Sep 12, 2026FactVenture organization websites (about, team, portfolio, thesis, news pages)
Team pagehttps://www.nlvpartners.com/team/
3 name/title pairs read
Sep 16, 2026FactVenture organization websites (about, team, portfolio, thesis, news pages)
Team pagehttps://www.nlvpartners.com/team/
3 name/title pairs read
Sep 12, 2026FactVenture organization websites (about, team, portfolio, thesis, news pages)
Venture funds reported9Mar 30, 2026FactSEC Form ADV monthly roster (registered + exempt reporting advisers)
Venture funds reported9Mar 28, 2024FactSEC Form ADV filing data 2011 to 2024 (every filing, Schedule D 7.B.(1) private funds, Schedules A/B)
WebsiteHTTP://WWW.NLVPARTNERS.COMMar 28, 2024FactSEC Form ADV filing data 2011 to 2024 (every filing, Schedule D 7.B.(1) private funds, Schedules A/B)
Site titleIndex - nlvpartners
title tag
Sep 16, 2026FactVenture organization websites (about, team, portfolio, thesis, news pages)
Site titleIndex - nlvpartners
title tag
Sep 12, 2026FactVenture organization websites (about, team, portfolio, thesis, news pages)
Year of incorporation2014Dec 3, 2014FactSEC EDGAR Form D data sets (quarterly)