Firms, funds, partners, companies and rounds from sworn filings, firm sites and announcements, kept as a graph with a date and a source on every edge. Facts, inferences and estimates are labelled as such. A fund target is never a close, GAV is never dry powder, and a round size is never an investor’s check.

Firms / Medical Excellence Capital, LLC

Medical Excellence Capital, LLC

Institutional venture firmUSmedexcelcap.comSEC venture capital fund adviser

MEC is an early-stage life sciences venture fund deploying precision capital to advance precision health innovations.

venture manager, reported GAV $146M across 1 vehicles

Importance
22
moderate
Active deployment
8
low
Emerging
0
low
Completeness
63
high
Freshness
100
high
Research priority
6
low
Identity and regulatory footprint
Headquarters
unknown
Office address
unknown
Business phone
(917) 512-5441adviserinfo.sec.gov
SEC adviser type
exempt reporting adviseradviserinfo.sec.gov
SEC exemption claimed
venture capital fund adviseradviserinfo.sec.govItem 2.B(1): advises solely venture capital funds
Latest Form ADV
Mar 6, 2026
Private funds reported
1 (1 venture capital funds)adviserinfo.sec.gov
Private fund gross assets
$146Madviserinfo.sec.govreported GAV of the funds, the adviser's own number; not fund size, not dry powder
Owners on Schedule A
Siracusa, LLC (Managing Member Of Medical Excellence Capital Llc And Medical Excellence Gp Llc), E; ICT Holdings Ltd. (Member Of Medical Excellence Capital Llc And Medical Excellence Gp Llc), A
business email
info@medexcelcap.commedexcelcap.compublished by the subject
business phone
(917) 512-5441adviserinfo.sec.govpublished by the subject
Stated thesis versus observed behaviour
2 observed deals
Stated (the firm’s website)
Sectors
ai, biotech, space
Stages
seed, series a, series b, early
Geography
not stated
Check size
not stated; DFX does not estimate checks from round sizes
Self-described
venture capital
Observed (from deals on record)
Stage at participation: no observed deals yet
Stage at first entry: no observed deals yet
Sectors
unknown 100%
lead rate n/afollow-on rate n/anew logos, 12 months 2
Funds and vehicles
1 reported
VehicleTypeVintageLifecycleReported GAVOwnersForm D soldLatest Form D
Medical Excellence Capital Partners, LPFundunknownUnknown$146M
Dec 16, 2024
11unknownunknown
GAV is the gross asset value the adviser reported on Form ADV for the vehicle, never the fund’s committed size and never dry powder. Form D sold is the amount sold as of the latest filing, never a final close.
Investment team
14 current, 0 departed
Joan Marie Mancini
Chief Financial Officer And Regulatory Contact Of Medical Excellence Capital Llc And Medical Excellence Gp Llc · since Nov 1, 2020
General partner
John Patrick Hornbostel
Counsel Of Medical Excellence Capital Llc And Medical Excellence Gp Llc · since Nov 1, 2020
General partner
John Prufeta
Managing Member Of Medical Excellence Capital Llc And Medical Excellence Gp Llc · since Aug 1, 2020
Managing partner
Olga Prufeta
Olga Prufeta has served as Limited Partner (LP) Liaison for Medical Excellence Capital (MEC) since its inception.
Partner
Investments on record
2 edges, 2 companies, 0 partner-attributed
CompanyRoundRolePartnerRound sizeThis investorDateSource
SYN001 – Arctic Therapeuticsportfolio listingunknownunknownunknownunknownSep 16, 2026Fact Venture organization websites (about, team, portfolio, thesis, news pages)
Trotana Therapeuticsportfolio listingunknownunknownunknownunknownSep 16, 2026Fact Venture organization websites (about, team, portfolio, thesis, news pages)
“This investor” is the amount disclosed for this investor alone; it is unknown unless a source said it. The round size is the whole round.
Co-investors
1 relationships from shared deals, counted for the whole firm
Limited partners
0 disclosed
No LP commitment on record. An LP edge needs a public disclosure with a quote: a pension report (see Limited partners for the plans read), a fund announcement naming the LP, or a Form ADV owner. The fund page carries the LP’s reported performance.
Timeline
2 dated events
  1. Dec 23, 2021
    Medical Excellence Capital, LLC first filed Form ADV (ERA, venture capital fund adviser exemption)
  2. Dec 23, 2021
    Medical Excellence Capital Partners, LP first reported on Form ADV by Medical Excellence Capital, LLC (Venture Capital Fund), GAV $104,300,000
Classification history
  1. Sep 12, 2026
    Institutional venture firm (confirmed, 95%, cls-1)
    venture manager, reported GAV $146M across 1 vehicles
Evidence
44 observations from 3 sources
Every observation behind this profile, with its source, date and class
FactValueEffectiveClassSource
Why admittedvc_exemption,vc_funds_reportedMar 6, 2026FactSEC Form ADV monthly roster (registered + exempt reporting advisers)
SEC exemption claimedventure_capital_fund_adviserMar 6, 2026FactSEC Form ADV monthly roster (registered + exempt reporting advisers)
SEC exemption claimedventure_capital_fund_adviserDec 16, 2024FactSEC Form ADV filing data 2011 to 2024 (every filing, Schedule D 7.B.(1) private funds, Schedules A/B)
SEC adviser typeexempt_reporting_adviserMar 6, 2026FactSEC Form ADV monthly roster (registered + exempt reporting advisers)
SEC adviser typeexempt_reporting_adviserDec 16, 2024FactSEC Form ADV filing data 2011 to 2024 (every filing, Schedule D 7.B.(1) private funds, Schedules A/B)
First Form ADV filing2021-12-23Dec 16, 2024FactSEC Form ADV filing data 2011 to 2024 (every filing, Schedule D 7.B.(1) private funds, Schedules A/B)
Adv history loadedadv-hist-1Sep 12, 2026FactSEC Form ADV filing data 2011 to 2024 (every filing, Schedule D 7.B.(1) private funds, Schedules A/B)
Latest Form ADV filing2026-03-06Mar 6, 2026FactSEC Form ADV monthly roster (registered + exempt reporting advisers)
Latest Form ADV filing2024-12-16Dec 16, 2024FactSEC Form ADV filing data 2011 to 2024 (every filing, Schedule D 7.B.(1) private funds, Schedules A/B)
SEC statusERA - ActiveMar 6, 2026FactSEC Form ADV monthly roster (registered + exempt reporting advisers)
SEC status effective2021-12-23Mar 6, 2026FactSEC Form ADV monthly roster (registered + exempt reporting advisers)
Venture share of reported funds1Dec 16, 2024FactSEC Form ADV filing data 2011 to 2024 (every filing, Schedule D 7.B.(1) private funds, Schedules A/B)
Business phone(917) 512-5441Mar 6, 2026FactSEC Form ADV monthly roster (registered + exempt reporting advisers)
Business phone(917) 512-5441Dec 16, 2024FactSEC Form ADV filing data 2011 to 2024 (every filing, Schedule D 7.B.(1) private funds, Schedules A/B)
Contact page urlhttps://medexcelcap.com/contact/
contact page linked from the home page
Sep 16, 2026FactVenture organization websites (about, team, portfolio, thesis, news pages)
DescriptionMEC is an early-stage life sciences venture fund deploying precision capital to advance precision health innovations.
meta description
Sep 16, 2026FactVenture organization websites (about, team, portfolio, thesis, news pages)
DescriptionMEC is an early-stage life sciences venture fund deploying precision capital to advance precision health innovations.
meta description
Sep 15, 2026FactVenture organization websites (about, team, portfolio, thesis, news pages)
Self-described typeventure_capital
A PURPOSE-BUILT VENTURE FIRM
Sep 16, 2026FactVenture organization websites (about, team, portfolio, thesis, news pages)
Self-described typeventure_capital
A PURPOSE-BUILT VENTURE FIRM
Sep 15, 2026FactVenture organization websites (about, team, portfolio, thesis, news pages)
Legal formLimited Liability CompanyMar 6, 2026FactSEC Form ADV monthly roster (registered + exempt reporting advisers)
Legal formLimited Liability CompanyDec 16, 2024FactSEC Form ADV filing data 2011 to 2024 (every filing, Schedule D 7.B.(1) private funds, Schedules A/B)
Portfolio pagehttps://medexcelcap.com/portfolio/
2 entries read
Sep 16, 2026FactVenture organization websites (about, team, portfolio, thesis, news pages)
Portfolio pagehttps://medexcelcap.com/portfolio/
2 entries read
Sep 15, 2026FactVenture organization websites (about, team, portfolio, thesis, news pages)
Private funds reported1Mar 6, 2026FactSEC Form ADV monthly roster (registered + exempt reporting advisers)
Private funds reported1Dec 16, 2024FactSEC Form ADV filing data 2011 to 2024 (every filing, Schedule D 7.B.(1) private funds, Schedules A/B)
Private fund gross assets (reported)$146MMar 6, 2026FactSEC Form ADV monthly roster (registered + exempt reporting advisers)
Private fund gross assets (reported)$146MDec 16, 2024FactSEC Form ADV filing data 2011 to 2024 (every filing, Schedule D 7.B.(1) private funds, Schedules A/B)
Stated sectorsai,biotech,space
sector words on the home page
Sep 16, 2026FactVenture organization websites (about, team, portfolio, thesis, news pages)
Stated sectorsai,biotech,space
sector words on the home page
Sep 15, 2026FactVenture organization websites (about, team, portfolio, thesis, news pages)
Stated stagesseed,series_a,series_b,early
stage words on the home page
Sep 16, 2026FactVenture organization websites (about, team, portfolio, thesis, news pages)
Stated stagesseed,series_a,series_b,early
stage words on the home page
Sep 15, 2026FactVenture organization websites (about, team, portfolio, thesis, news pages)
Team pagehttps://medexcelcap.com/team/
11 name/title pairs read
Sep 16, 2026FactVenture organization websites (about, team, portfolio, thesis, news pages)
Team pagehttps://medexcelcap.com/team/
8 name/title pairs read
Sep 15, 2026FactVenture organization websites (about, team, portfolio, thesis, news pages)
Venture funds reported1Mar 6, 2026FactSEC Form ADV monthly roster (registered + exempt reporting advisers)
Venture funds reported1Dec 16, 2024FactSEC Form ADV filing data 2011 to 2024 (every filing, Schedule D 7.B.(1) private funds, Schedules A/B)
Websitehttps://www.medexcelcap.comDec 16, 2024FactSEC Form ADV filing data 2011 to 2024 (every filing, Schedule D 7.B.(1) private funds, Schedules A/B)
Site titleMedical Excellence Capital
title tag
Sep 16, 2026FactVenture organization websites (about, team, portfolio, thesis, news pages)
Site titleMedical Excellence Capital
title tag
Sep 15, 2026FactVenture organization websites (about, team, portfolio, thesis, news pages)